Wednesday, June 27, 2018

Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids by R.Durbin, S.Eddy, A.Krogh, G.Mitchison

Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids by R.Durbin, S.Eddy, A.Krogh, G.Mitchison


Probablistic models are becoming increasingly important in analyzing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analyzing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it is accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time presents the state of the art in this new and important field.

Product details
Paperback: 356 pages
Publisher: Cambridge University Press; 1 edition (May 13, 1998)
Language: English
ISBN-10: 0521629713
ISBN-13: 978-0521629713
Product Dimensions: 6.8 x 0.8 x 9.7 inches

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